Patients are participating in inflammation and immune system research around the world

We currently have a number of clinical trials and research studies seeking patients managing various inflammation and immune system disorders. We can help find trials and research studies near you and may help you to get access to those opportunities.

Find a medical research participation opportunity that is right for you!

Inflammation and immune system clinical trials and research studies

What is inflammation and immune system?

The immune system is a complex network made up of different types of organs, cells, proteins and chemicals that defends the body against infection (bacteria, viruses, fungi), foreign bodies like splinters, and abnormal cells (cancer). Components of the immune system include white blood cells, antibodies, the lymphatic system, the spleen and the bone marrow.

The immune system is constantly in surveillance mode and when a “threat” is detected, the immune system mounts a response, which can include inducing inflammation (eg. swelling, redness and warmth at the site of an infection), fever or creating antibodies. In certain situations, the immune system “remembers” this response so when the same threat is detected in the future, the body can more quickly respond to it.

Having an overactive immune system is associated with disorders such as autoimmune diseases (arthritis, lupus) and allergies. Here, the immune system mounts an overly strong response against normal cells or environmental particles. The causes of an overactive immune system still are not well understood. On the other hand, an under-active immune system (also called immunodeficiency) does not function normally and increases vulnerability to infections. This can be inherited (i.e. a genetic disorder), caused by medications that suppress the immune system (such as corticosteroids or chemotherapy) or be the result of a disease (such as HIV/AIDS).

Where is inflammation and immune system research now?

The immune system is large and complex, and there is a lot of research being undertaken around the world to understand how the immune system develops, how it reacts to certain “threats,” and how to harness it to fight disease and cancer (i.e. immunotherapy and vaccines). There is considerable interest in understanding the interplay between the immune system, inflammation and parts of the body such as the brain and the gut.

In terms of overactive immune system related disorders, research is focused on understanding the causes to form better prevention strategies, as well as on improved management protocols and new treatments. For inherited immunodeficiency disorders, researchers are investigating using next generation technologies such as gene therapy to treat these disorders.

How can I get involved in inflammation and immune system research?

Participating in inflammatory disorders and the immune system research and clinical trials may be a method to access the latest treatment drugs or it may help pave the way in developing new interventions and treatments that will benefit others. There are a large number of clinical trials and research studies undertaken each year to understand, prevent and treat inflammatory and the immune system disorders.

Participants participated for inflammation and immune system trials around the world

Opin’s direct-to-patient approach can reduce participant timelines to weeks, not months.

Number of Participants

required for trials.

* out of total trials participating

Inflammation and immune system clinical trials and research studies around the world

821 trials

Phase 1

769 trials

Phase 2

260 trials

Phase 3

168 trials

Phase 4

1,652 trials


Leading areas of inflammation and immune system research

Types of inflammation and immune system